Detecting Rare Variant Associations by Identity-by-Descent Mapping in Case-Control Studies

Identity-by-descent (IBD) mapping tests whether cases share more segments of IBD around a putative causal variant than do controls. These segments of IBD can be accurately detected from genome-wide SNP data. We investigate the power of IBD mapping relative to that of SNP association testing for geno...

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Detalles Bibliográficos
Autores principales: Browning, Sharon R., Thompson, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316661/
https://www.ncbi.nlm.nih.gov/pubmed/22267498
http://dx.doi.org/10.1534/genetics.111.136937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316661/
https://www.ncbi.nlm.nih.gov/pubmed/22267498
http://dx.doi.org/10.1534/genetics.111.136937

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