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Detecting Rare Variant Associations by Identity-by-Descent Mapping in Case-Control Studies
Identity-by-descent (IBD) mapping tests whether cases share more segments of IBD around a putative causal variant than do controls. These segments of IBD can be accurately detected from genome-wide SNP data. We investigate the power of IBD mapping relative to that of SNP association testing for geno...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316661/ https://www.ncbi.nlm.nih.gov/pubmed/22267498 http://dx.doi.org/10.1534/genetics.111.136937 |