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Mitochondrial Dysfunction and Adipogenic Reduction by Prohibitin Silencing in 3T3-L1 Cells

Increase in mitochondrial biogenesis has been shown to accompany brown and white adipose cell differentiation. Prohibitins (PHBs), comprised of two evolutionarily conserved proteins, prohibitin-1 (PHB1) and prohibitin-2 (PHB2), are present in a high molecular-weight complex in the inner membrane of...

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Detalles Bibliográficos
Autores principales: Liu, Dong, Lin, Yiming, Kang, Ting, Huang, Bo, Xu, Wei, Garcia-Barrio, Minerva, Olatinwo, Moshood, Matthews, Roland, Chen, Y. Eugene, Thompson, Winston E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316679/
https://www.ncbi.nlm.nih.gov/pubmed/22479600
http://dx.doi.org/10.1371/journal.pone.0034315