Phenotypic and Functional Properties of Helios(+) Regulatory T Cells

Helios, an Ikaros family transcription factor, is preferentially expressed at the mRNA and protein level in regulatory T cells. Helios expression previously appeared to be restricted to thymic-derived Treg. Consistent with recent data, we show here that Helios expression is inducible in vitro under...

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Detalles Bibliográficos
Autores principales: Zabransky, Daniel J., Nirschl, Christopher J., Durham, Nicholas M., Park, Ben V., Ceccato, Christina M., Bruno, Tullia C., Tam, Ada J., Getnet, Derese, Drake, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316700/
https://www.ncbi.nlm.nih.gov/pubmed/22479644
http://dx.doi.org/10.1371/journal.pone.0034547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316700/
https://www.ncbi.nlm.nih.gov/pubmed/22479644
http://dx.doi.org/10.1371/journal.pone.0034547

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