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A Quantitative Spatial Proteomics Analysis of Proteome Turnover in Human Cells

Measuring the properties of endogenous cell proteins, such as expression level, subcellular localization, and turnover rates, on a whole proteome level remains a major challenge in the postgenome era. Quantitative methods for measuring mRNA expression do not reliably predict corresponding protein le...

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Detalles Bibliográficos
Autores principales: Boisvert, François-Michel, Ahmad, Yasmeen, Gierliński, Marek, Charrière, Fabien, Lamont, Douglas, Scott, Michelle, Barton, Geoff, Lamond, Angus I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316722/
https://www.ncbi.nlm.nih.gov/pubmed/21937730
http://dx.doi.org/10.1074/mcp.M111.011429