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A Framework for Intelligent Data Acquisition and Real-Time Database Searching for Shotgun Proteomics

In the analysis of complex peptide mixtures by MS-based proteomics, many more peptides elute at any given time than can be identified and quantified by the mass spectrometer. This makes it desirable to optimally allocate peptide sequencing and narrow mass range quantification events. In computer sci...

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Detalles Bibliográficos
Autores principales: Graumann, Johannes, Scheltema, Richard A., Zhang, Yong, Cox, Jürgen, Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316723/
https://www.ncbi.nlm.nih.gov/pubmed/22171319
http://dx.doi.org/10.1074/mcp.M111.013185