Cargando…

Characterization of MRFAP1 Turnover and Interactions Downstream of the NEDD8 Pathway

The NEDD8-Cullin E3 ligase pathway plays an important role in protein homeostasis, in particular the degradation of cell cycle regulators and transcriptional control networks. To characterize NEDD8-cullin target proteins, we performed a quantitative proteomic analysis of cells treated with MLN4924,...

Descripción completa

Detalles Bibliográficos
Autores principales: Larance, Mark, Kirkwood, Kathryn J., Xirodimas, Dimitris P., Lundberg, Emma, Uhlen, Mathias, Lamond, Angus I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316733/
https://www.ncbi.nlm.nih.gov/pubmed/22038470
http://dx.doi.org/10.1074/mcp.M111.014407