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Characterization of MRFAP1 Turnover and Interactions Downstream of the NEDD8 Pathway
The NEDD8-Cullin E3 ligase pathway plays an important role in protein homeostasis, in particular the degradation of cell cycle regulators and transcriptional control networks. To characterize NEDD8-cullin target proteins, we performed a quantitative proteomic analysis of cells treated with MLN4924,...
Autores principales: | Larance, Mark, Kirkwood, Kathryn J., Xirodimas, Dimitris P., Lundberg, Emma, Uhlen, Mathias, Lamond, Angus I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316733/ https://www.ncbi.nlm.nih.gov/pubmed/22038470 http://dx.doi.org/10.1074/mcp.M111.014407 |
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