Host gene targets for novel influenza therapies elucidated by high‐throughput RNA interference screens

Influenza virus encodes only 11 viral proteins but replicates in a broad range of avian and mammalian species by exploiting host cell functions. Genome‐wide RNA interference (RNAi) has proven to be a powerful tool for identifying the host molecules that participate in each step of virus replication....

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Detalles Bibliográficos
Autores principales: Meliopoulos, Victoria A., Andersen, Lauren E., Birrer, Katherine F., Simpson, Kaylene J., Lowenthal, John W., Bean, Andrew G. D., Stambas, John, Stewart, Cameron R., Tompkins, S. Mark, van Beusechem, Victor W., Fraser, Iain, Mhlanga, Musa, Barichievy, Samantha, Smith, Queta, Leake, Devin, Karpilow, Jon, Buck, Amy, Jona, Ghil, Tripp, Ralph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316894/
https://www.ncbi.nlm.nih.gov/pubmed/22247330
http://dx.doi.org/10.1096/fj.11-193466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316894/
https://www.ncbi.nlm.nih.gov/pubmed/22247330
http://dx.doi.org/10.1096/fj.11-193466

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