Aggregation of αSynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons

Fibrillar αSynuclein is the major constituent of Lewy bodies and Lewy neurites, the protein deposits characteristic for Parkinson’s disease (PD). Multiplications of the αSynuclein gene, as well as point mutations cause familial PD. However, the exact role of αSynuclein in neurodegeneration remains u...

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Detalles Bibliográficos
Autores principales: Taschenberger, Grit, Garrido, Manuel, Tereshchenko, Yuliya, Bähr, Mathias, Zweckstetter, Markus, Kügler, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316935/
https://www.ncbi.nlm.nih.gov/pubmed/22167382
http://dx.doi.org/10.1007/s00401-011-0926-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316935/
https://www.ncbi.nlm.nih.gov/pubmed/22167382
http://dx.doi.org/10.1007/s00401-011-0926-8

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