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Screening and Evaluation of Deleterious SNPs in APOE Gene of Alzheimer's Disease

Introduction. Apolipoprotein E (APOE) is an important risk factor for Alzheimer's disease (AD) and is present in 30–50% of patients who develop late-onset AD. Several single-nucleotide polymorphisms (SNPs) are present in APOE gene which act as the biomarkers for exploring the genetic basis of t...

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Detalles Bibliográficos
Autores principales: Masoodi, Tariq Ahmad, Al Shammari, Sulaiman A., Al-Muammar, May N., Alhamdan, Adel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317072/
https://www.ncbi.nlm.nih.gov/pubmed/22530123
http://dx.doi.org/10.1155/2012/480609