GRP78 Protein Expression in Ovarian Cancer Patients and Perspectives for a Drug-Targeting Approach

Glucose-regulated protein of 78 kD (GRP78) is a chaperone protein mainly located in the endoplasmic reticulum (ER). This protein is normally present at low levels in adult cells but its expression is triggered by ER stress including glucose deprivation and hypoxia. In tumor cells, it is overexpresse...

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Detalles Bibliográficos
Autores principales: Delie, Florence, Petignat, Patrick, Cohen, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317113/
https://www.ncbi.nlm.nih.gov/pubmed/22481929
http://dx.doi.org/10.1155/2012/468615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317113/
https://www.ncbi.nlm.nih.gov/pubmed/22481929
http://dx.doi.org/10.1155/2012/468615

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