Dopamine D(2) Receptor-Mediated Heterologous Sensitization of AC5 Requires Signalosome Assembly

Chronic dopamine receptor activation is implicated in several central nervous system disorders. Although acute activation of Gα (i)-coupled D(2) dopamine receptors inhibits adenylyl cyclase, persistent activation enhances adenylyl cyclase activity, a phenomenon called heterologous sensitization. Pre...

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Detalles Bibliográficos
Autores principales: Ejendal, Karin F. K., Dessauer, Carmen W., Hébert, Terence E., Watts, Val J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317181/
https://www.ncbi.nlm.nih.gov/pubmed/22523680
http://dx.doi.org/10.1155/2012/210324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317181/
https://www.ncbi.nlm.nih.gov/pubmed/22523680
http://dx.doi.org/10.1155/2012/210324

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