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Exendin-4 Protects MIN6 Cells from t-BHP-Induced Apoptosis via IRE1-JNK-Caspase-3 Signaling

Objectives. This study aimed to explore the effect of exendin-4 on t-BHP-induced apoptosis in pancreatic β cells and the mechanism of action. Methods. Murine MIN6 pancreatic β cells were treated with exendin-4 in the presence or absence of tert-butyl hydroperoxide (t-BHP). Cell survival was assessed...

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Detalles Bibliográficos
Autores principales:	Chen, Wen-Jia, Wang, Lin-Xi, Wang, Yan-Ping, Chen, Zhou, Liu, Xiao-Ying, Liu, Xiao-Hong, Liu, Li-Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317221/ https://www.ncbi.nlm.nih.gov/pubmed/22518128 http://dx.doi.org/10.1155/2012/549081

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