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Rodent Animal Models for Surrogate Analysis of Cell Therapy in Acute Liver Failure
Without therapeutic intervention acute liver failure (ALF) is the consequence of a progredient destruction of the liver parenchyma due to metabolic exhaustion of the hepatocytes. Perivenous hepatocytes are responsible for the detoxification of noxious compounds via the cytochrome P450 enzyme system....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317270/ https://www.ncbi.nlm.nih.gov/pubmed/22485094 http://dx.doi.org/10.3389/fphys.2012.00078 |