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Rodent Animal Models for Surrogate Analysis of Cell Therapy in Acute Liver Failure

Without therapeutic intervention acute liver failure (ALF) is the consequence of a progredient destruction of the liver parenchyma due to metabolic exhaustion of the hepatocytes. Perivenous hepatocytes are responsible for the detoxification of noxious compounds via the cytochrome P450 enzyme system....

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Detalles Bibliográficos
Autores principales: Christ, Bruno, Brückner, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317270/
https://www.ncbi.nlm.nih.gov/pubmed/22485094
http://dx.doi.org/10.3389/fphys.2012.00078