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Regulation of p73 activity by post-translational modifications

The transcription factor p73 is a member of the p53 family that can be expressed as at least 24 different isoforms with pro- or anti-apoptotic attributes. The TAp73 isoforms are expressed from an upstream promoter and are regarded as bona fide tumor suppressors; they can induce cell cycle arrest/apo...

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Detalles Bibliográficos
Autores principales: Conforti, F, Sayan, A E, Sreekumar, R, Sayan, B S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317350/
https://www.ncbi.nlm.nih.gov/pubmed/22419114
http://dx.doi.org/10.1038/cddis.2012.27