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Computational Identification and Modeling of Crosstalk between Phosphorylation, O-β-glycosylation and Methylation of FoxO3 and Implications for Cancer Therapeutics

FoxO3 is a member of the forkhead class of transcription factors and plays a major role in the regulation of diverse cellular processes, including cell cycle arrest, DNA repair, and protection from stress stimuli by detoxification of reactive oxygen species. In addition, FoxO3 is a tumor suppressor...

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Detalles Bibliográficos
Autores principales: Butt, Azeem Mehmood, Feng, Dandan, Idrees, Muhammad, Tong, Yigang, Lu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317383/
https://www.ncbi.nlm.nih.gov/pubmed/22489133
http://dx.doi.org/10.3390/ijms13032918