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Blockade of Fatty Acid Synthase Triggers Significant Apoptosis in Mantle Cell Lymphoma
Fatty acid synthase (FASN), a key player in the de novo synthetic pathway of long-chain fatty acids, has been shown to contribute to the tumorigenesis in various types of solid tumors. We here report that FASN is highly and consistently expressed in mantle cell lymphoma (MCL), an aggressive form of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317445/ https://www.ncbi.nlm.nih.gov/pubmed/22485149 http://dx.doi.org/10.1371/journal.pone.0033738 |