Blockade of Fatty Acid Synthase Triggers Significant Apoptosis in Mantle Cell Lymphoma

Fatty acid synthase (FASN), a key player in the de novo synthetic pathway of long-chain fatty acids, has been shown to contribute to the tumorigenesis in various types of solid tumors. We here report that FASN is highly and consistently expressed in mantle cell lymphoma (MCL), an aggressive form of...

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Detalles Bibliográficos
Autores principales: Gelebart, Pascal, Zak, Zoulika, Anand, Mona, Belch, Andrew, Lai, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317445/
https://www.ncbi.nlm.nih.gov/pubmed/22485149
http://dx.doi.org/10.1371/journal.pone.0033738

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