Antinociceptive Effect of Rat D-Serine Racemase Inhibitors, L-Serine-O-Sulfate, and L-Erythro-3-Hydroxyaspartate in an Arthritic Pain Model

N-methyl-D-aspartic acid receptor (NMDAr) activation requires the presence of D-serine, synthesized from L-serine by a pyridoxal 5′-phosphate-dependent serine racemase (SR). D-serine levels can be lowered by inhibiting the racemization of L-serine. L-serine-O-sulfate (LSOS) and L-erythro-3-hydroxyas...

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Detalles Bibliográficos
Autores principales: Laurido, Claudio, Hernández, Alejandro, Pelissier, Teresa, Constandil, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317629/
https://www.ncbi.nlm.nih.gov/pubmed/22536130
http://dx.doi.org/10.1100/2012/279147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317629/
https://www.ncbi.nlm.nih.gov/pubmed/22536130
http://dx.doi.org/10.1100/2012/279147

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