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Monitoring of Regulatory T Cell Frequencies and Expression of CTLA-4 on T Cells, before and after DC Vaccination, Can Predict Survival in GBM Patients

PURPOSE: Dendritic cell (DC) vaccines have recently emerged as an innovative therapeutic option for glioblastoma patients. To identify novel surrogates of anti-tumor immune responsiveness, we studied the dynamic expression of activation and inhibitory markers on peripheral blood lymphocyte (PBL) sub...

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Detalles Bibliográficos
Autores principales: Fong, Brendan, Jin, Richard, Wang, Xiaoyan, Safaee, Michael, Lisiero, Dominique N., Yang, Isaac, Li, Gang, Liau, Linda M., Prins, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317661/
https://www.ncbi.nlm.nih.gov/pubmed/22485134
http://dx.doi.org/10.1371/journal.pone.0032614