Phage Display Approaches for the Isolation of Monoclonal Antibodies Against Dengue Virus Envelope Domain III from Human and Mouse Derived Libraries

Domain III of the dengue virus envelope protein (EDIII, aa295-395) has an immunoglobulin fold and is the proposed receptor-binding domain of the virus. Previous studies have shown that monoclonal antibodies against EDIII can be neutralizing and have therapeutic potential. Here, cloned Fab-phage libr...

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Detalles Bibliográficos
Autores principales: Moreland, Nicole J., Susanto, Patricia, Lim, Elfin, Tay, Moon Y. F., Rajamanonmani, Ravikumar, Hanson, Brendon J., Vasudevan, Subhash G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317677/
https://www.ncbi.nlm.nih.gov/pubmed/22489114
http://dx.doi.org/10.3390/ijms13032618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317677/
https://www.ncbi.nlm.nih.gov/pubmed/22489114
http://dx.doi.org/10.3390/ijms13032618

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