BDMC33, A Curcumin Derivative Suppresses Inflammatory Responses in Macrophage-Like Cellular System: Role of Inhibition in NF-κB and MAPK Signaling Pathways

Our preliminary screening has shown that curcumin derivative BDMC33 [2,6-bis(2,5-dimethoxybenzylidene)cyclohexanone] exerted promising nitric oxide inhibitory activity in activated macrophages. However, the molecular basis and mechanism for its pharmacological action is yet to be elucidated. The aim...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Ka-Heng, Chow, Yuh-Lit, Sharmili, Vidyadaran, Abas, Faridah, Alitheen, Noorjahan Banu Mohamed, Shaari, Khozirah, Israf, Daud Ahmad, Lajis, Nordin Haji, Syahida, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317699/
https://www.ncbi.nlm.nih.gov/pubmed/22489138
http://dx.doi.org/10.3390/ijms13032985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317699/
https://www.ncbi.nlm.nih.gov/pubmed/22489138
http://dx.doi.org/10.3390/ijms13032985

Ejemplares similares