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Generating Aptamers by Cell-SELEX for Applications in Molecular Medicine

Aptamers are single-stranded oligonucleotides of DNA or RNA that bind to target molecules with high affinity and specificity. Typically, aptamers are generated by an iterative selection process, called systematic evolution of ligands by exponential enrichment (SELEX). Recent advancements in SELEX te...

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Detalles Bibliográficos
Autores principales: Ye, Mao, Hu, Jun, Peng, Minyuan, Liu, Jing, Liu, Jun, Liu, Huixia, Zhao, Xielan, Tan, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317715/
https://www.ncbi.nlm.nih.gov/pubmed/22489154
http://dx.doi.org/10.3390/ijms13033341