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Autophagy in Premature Senescent Cells Is Activated via AMPK Pathway

Autophagy is a highly regulated intracellular process involved in the turnover of most cellular constituents and in the maintenance of cellular homeostasis. In this study, we show that the activity of autophagy increases in H(2)O(2) or RasV12-induced senescent fibroblasts. Inhibiting autophagy promo...

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Detalles Bibliográficos
Autores principales: Guo, Liujing, Xie, Bushan, Mao, Zebin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317728/
https://www.ncbi.nlm.nih.gov/pubmed/22489168
http://dx.doi.org/10.3390/ijms13033563