The Effect of Osmolytes on Protein Fibrillation

Osmolytes are small molecules that are exploited by cells as a protective system against stress conditions. They favour compact protein states which makes them stabilize globular proteins in vitro and promote folding. Conversely, this preference for compact states promotes aggregation of unstructure...

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Detalles Bibliográficos
Autores principales: Macchi, Francesca, Eisenkolb, Maike, Kiefer, Hans, Otzen, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317744/
https://www.ncbi.nlm.nih.gov/pubmed/22489184
http://dx.doi.org/10.3390/ijms13033801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317744/
https://www.ncbi.nlm.nih.gov/pubmed/22489184
http://dx.doi.org/10.3390/ijms13033801

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