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The Effect of Osmolytes on Protein Fibrillation
Osmolytes are small molecules that are exploited by cells as a protective system against stress conditions. They favour compact protein states which makes them stabilize globular proteins in vitro and promote folding. Conversely, this preference for compact states promotes aggregation of unstructure...
Autores principales: | Macchi, Francesca, Eisenkolb, Maike, Kiefer, Hans, Otzen, Daniel E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317744/ https://www.ncbi.nlm.nih.gov/pubmed/22489184 http://dx.doi.org/10.3390/ijms13033801 |
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