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Development of a Unique Small Molecule Modulator of CXCR4

BACKGROUND: Metastasis, the spread and growth of tumor cells to distant organ sites, represents the most devastating attribute and plays a major role in the morbidity and mortality of cancer. Inflammation is crucial for malignant tumor transformation and survival. Thus, blocking inflammation is expe...

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Detalles Bibliográficos
Autores principales: Liang, Zhongxing, Zhan, Weiqiang, Zhu, Aizhi, Yoon, Younghyoun, Lin, Songbai, Sasaki, Maiko, Klapproth, Jan-Michael A., Yang, Hua, Grossniklaus, Hans E., Xu, Jianguo, Rojas, Mauricio, Voll, Ronald J., Goodman, Mark M., Arrendale, Richard F., Liu, Jin, Yun, C. Chris, Snyder, James P., Liotta, Dennis C., Shim, Hyunsuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317778/
https://www.ncbi.nlm.nih.gov/pubmed/22485156
http://dx.doi.org/10.1371/journal.pone.0034038