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A link between mitotic entry and membrane growth suggests a novel model for cell size control

Addition of new membrane to the cell surface by membrane trafficking is necessary for cell growth. In this paper, we report that blocking membrane traffic causes a mitotic checkpoint arrest via Wee1-dependent inhibitory phosphorylation of Cdk1. Checkpoint signals are relayed by the Rho1 GTPase, prot...

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Detalles Bibliográficos
Autores principales: Anastasia, Steph D., Nguyen, Duy Linh, Thai, Vu, Meloy, Melissa, MacDonough, Tracy, Kellogg, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317797/
https://www.ncbi.nlm.nih.gov/pubmed/22451696
http://dx.doi.org/10.1083/jcb.201108108