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Nucleophosmin/B23 activates Aurora A at the centrosome through phosphorylation of serine 89

Aurora A (AurA) is a major mitotic protein kinase involved in centrosome maturation and spindle assembly. Nucleophosmin/B23 (NPM) is a pleiotropic nucleolar protein involved in a variety of cellular processes including centrosome maturation. In the present study, we report that NPM is a strong activ...

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Detalles Bibliográficos
Autores principales: Reboutier, David, Troadec, Marie-Bérengère, Cremet, Jean-Yves, Fukasawa, Kenji, Prigent, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317798/
https://www.ncbi.nlm.nih.gov/pubmed/22451695
http://dx.doi.org/10.1083/jcb.201107134