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Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism

Mesenchymal cell migration as exhibited by fibroblasts is distinct from amoeboid cell migration and is characterized by dynamic competition among multiple protrusions, which determines directional persistence and responses to spatial cues. Localization of phosphoinositide 3-kinase (PI3K) signaling i...

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Detalles Bibliográficos
Autores principales: Welf, Erik S., Ahmed, Shoeb, Johnson, Heath E., Melvin, Adam T., Haugh, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317800/
https://www.ncbi.nlm.nih.gov/pubmed/22472441
http://dx.doi.org/10.1083/jcb.201108152