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Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism
Mesenchymal cell migration as exhibited by fibroblasts is distinct from amoeboid cell migration and is characterized by dynamic competition among multiple protrusions, which determines directional persistence and responses to spatial cues. Localization of phosphoinositide 3-kinase (PI3K) signaling i...
Autores principales: | Welf, Erik S., Ahmed, Shoeb, Johnson, Heath E., Melvin, Adam T., Haugh, Jason M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317800/ https://www.ncbi.nlm.nih.gov/pubmed/22472441 http://dx.doi.org/10.1083/jcb.201108152 |
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