Cargando…

Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy

The mouse zona pellucida is composed of three glycoproteins (ZP1, ZP2, and ZP3), of which ZP2 is proteolytically cleaved after gamete fusion to prevent polyspermy. This cleavage is associated with exocytosis of cortical granules that are peripherally located subcellular organelles unique to ovulated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Burkart, Anna D., Xiong, Bo, Baibakov, Boris, Jiménez-Movilla, Maria, Dean, Jurrien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317803/ https://www.ncbi.nlm.nih.gov/pubmed/22472438 http://dx.doi.org/10.1083/jcb.201112094

Ejemplares similares

Ovastacin: An oolemma protein that cleaves the zona pellucida to prevent polyspermy
por: Kang, Inyoung, et al.
Publicado: (2023)

Human sperm bind to the N-terminal domain of ZP2 in humanized zonae pellucidae in transgenic mice
por: Baibakov, Boris, et al.
Publicado: (2012)

A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans
por: Avella, Matteo A., et al.
Publicado: (2014)

A Unique Egg Cortical Granule Localization Motif Is Required for Ovastacin Sequestration to Prevent Premature ZP2 Cleavage and Ensure Female Fertility in Mice
por: Xiong, Bo, et al.
Publicado: (2017)

Egg cortical granule N-acetylglucosaminidase is required for the mouse zona block to polyspermy
Publicado: (1993)

ZP4 confers structural properties to the zona pellucida essential for embryo development
por: Lamas-Toranzo, Ismael, et al.
Publicado: (2019)

ZP4 Is Present in Murine Zona Pellucida and Is Not Responsible for the Specific Gamete Interaction
por: Izquierdo-Rico, Mª José, et al.
Publicado: (2021)

Structural Analysis of Peptide-Analogues of Human Zona Pellucida ZP1 Protein with Amyloidogenic Properties: Insights into Mammalian Zona Pellucida Formation
por: Louros, Nikolaos N., et al.
Publicado: (2013)

The Hinge Region of Bovine Zona Pellucida Glycoprotein ZP3 Is Involved in the Formation of the Sperm-Binding Active ZP3/ZP4 Complex
por: Suzuki, Kaori, et al.
Publicado: (2015)

Molecular Evolutionary Analysis of Nematode Zona Pellucida (ZP) Modules Reveals Disulfide-Bond Reshuffling and Standalone ZP-C Domains
por: Weadick, Cameron J
Publicado: (2020)

Whole-Depth Change in Bovine Zona Pellucida Biomechanics after Fertilization: How Relevant in Hindering Polyspermy?
por: Papi, Massimiliano, et al.
Publicado: (2012)

N-Glycosylation Site in the Middle Region Is Involved in the Sperm-Binding Activity of Bovine Zona Pellucida Glycoproteins ZP3 and ZP4
por: Dilimulati, Kamila, et al.
Publicado: (2023)

Monoclonal antibodies as probes of the distribution of ZP-2, the major sulfated glycoprotein of the murine zona pellucida
Publicado: (1984)

Zona Pellucida Protein 2 (ZP2) Is Expressed in Colon Cancer and Promotes Cell Proliferation
por: Kraus, Dominik, et al.
Publicado: (2021)

'ZP domain' of human zona pellucida glycoprotein-1 binds to human spermatozoa and induces acrosomal exocytosis
por: Ganguly, Anasua, et al.
Publicado: (2010)

A heterozygous ZP2 mutation causes zona pellucida defects and female infertility in mouse and human
por: Liu, Sai-Li, et al.
Publicado: (2023)

New Insights into the Mammalian Egg Zona Pellucida
por: Moros-Nicolás, Carla, et al.
Publicado: (2021)

Identification of distinctive interdomain interactions among ZP-N, ZP-C and other domains of zona pellucida glycoproteins underlying association of chicken egg-coat matrix
por: Okumura, Hiroki, et al.
Publicado: (2015)

New insights into the role of microheterogeneity of ZP3 during structural maturation of the avian equivalent of mammalian zona pellucida
por: Okumura, Hiroki, et al.
Publicado: (2023)

Identification of zona pellucida defects revealed a novel loss-of-function mutation in ZP2 in humans and rats
por: Zeng, Jun, et al.
Publicado: (2023)

Study on the zona pellucida 4 (ZP4) gene sequence and its expression in the ovaries of patients with polycystic ovary syndrome
por: Meczekalski, B., et al.
Publicado: (2015)

The preclinical evaluation of immunocontraceptive vaccines based on canine zona pellucida 3 (cZP3) in a mouse model
por: Wang, Ying, et al.
Publicado: (2018)

Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes
por: Cheeseman, Liam P., et al.
Publicado: (2016)

Sperm-binding regions on bovine egg zona pellucida glycoprotein ZP4 studied in a solid supported form on plastic plate
por: Dilimulati, Kamila, et al.
Publicado: (2021)

The C-terminal region of OVGP1 remodels the zona pellucida and modifies fertility parameters
por: Algarra, B., et al.
Publicado: (2016)

Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice
por: Shin, Seung-Wook, et al.
Publicado: (2017)

Female fertility and the zona pellucida
por: Wassarman, Paul M, et al.
Publicado: (2022)

Identification of a Novel TGF-β-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-β-Receptor-3 (TGFR-3)
por: Diestel, Uschi, et al.
Publicado: (2013)

Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis
por: Vogt, Edgar-John, et al.
Publicado: (2019)

Silkworm recombinant bovine zona pellucida protein 4 (bZP4) as a potential female immunocontraceptive antigen; impaired sperm-oocyte interaction and ovarian dysfunction
por: TATEMATSU, Ken-ichiro, et al.
Publicado: (2021)

Amyloid Properties of the Mouse Egg Zona Pellucida
por: Egge, Nathan, et al.
Publicado: (2015)

The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin
por: Brunati, Martina, et al.
Publicado: (2015)

Ovastacin cuts off sperm binding
por: Short, Ben
Publicado: (2012)

Author Correction: Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis
por: Vogt, Edgar-John, et al.
Publicado: (2019)

Mammalian spermatozoa and cumulus cells bind to a 3D model generated by recombinant zona pellucida protein-coated beads
por: Hamze, Julieta Gabriela, et al.
Publicado: (2019)

Intactness of zona pellucida does not affect the secretion of a trypsin-like protease from mouse blastocyst.
por: Hwang, S., et al.
Publicado: (2000)

Availability of Empty Zona Pellucida for Generating Embryonic Chimeras
por: Park, Chi-Hun, et al.
Publicado: (2015)

Characterization of oocyte retrieval cycles with empty zona pellucida
por: Oride, Aki, et al.
Publicado: (2017)

Evolution and multiple origins of zona pellucida genes in vertebrates
por: Feng, Jin-Mei, et al.
Publicado: (2018)

Visco-Hyperelastic Characterization of the Equine Immature Zona Pellucida
por: Ficarella, Elisa, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_onvuu0rkpfacs0ri23ej6jt4iq