Actin polymerization stabilizes α4β1 integrin anchors that mediate monocyte adhesion

Leukocytes arrested on inflamed endothelium via integrins are subjected to force imparted by flowing blood. How leukocytes respond to this force and resist detachment is poorly understood. Live-cell imaging with Lifeact-transfected U937 cells revealed that force triggers actin polymerization at upst...

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Detalles Bibliográficos
Autores principales: Rullo, Jacob, Becker, Henry, Hyduk, Sharon J., Wong, Janice C., Digby, Genevieve, Arora, Pamma D., Cano, Adrianet Puig, Hartwig, John, McCulloch, Christopher A., Cybulsky, Myron I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317807/
https://www.ncbi.nlm.nih.gov/pubmed/22472442
http://dx.doi.org/10.1083/jcb.201107140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317807/
https://www.ncbi.nlm.nih.gov/pubmed/22472442
http://dx.doi.org/10.1083/jcb.201107140

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