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Nonheritable Cellular Variability Accelerates the Evolutionary Processes of Cancer
Recent cancer studies emphasize that genetic and heritable epigenetic changes drive the evolutionary rate of cancer progression and drug resistance. We discuss the ways in which nonheritable aspects of cellular variability may significantly increase evolutionary rate. Nonheritable variability arises...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317895/ https://www.ncbi.nlm.nih.gov/pubmed/22509130 http://dx.doi.org/10.1371/journal.pbio.1001296 |