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Investigation of the Proteolytic Functions of an Expanded Cercarial Elastase Gene Family in Schistosoma mansoni

BACKGROUND: Cercarial elastase is the major invasive larval protease in Schistosoma mansoni, a parasitic blood fluke, and is essential for host skin invasion. Genome sequence analysis reveals a greatly expanded family of cercarial elastase gene isoforms in Schistosoma mansoni. This expansion appears...

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Detalles Bibliográficos
Autores principales: Ingram, Jessica R., Rafi, Salma B., Eroy-Reveles, A. Alegra, Ray, Manisha, Lambeth, Laura, Hsieh, Ivy, Ruelas, Debbie, Lim, K. C., Sakanari, Judy, Craik, Charles S., Jacobson, Matthew P., McKerrow, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317910/
https://www.ncbi.nlm.nih.gov/pubmed/22509414
http://dx.doi.org/10.1371/journal.pntd.0001589