Natural Terpenes Prevent Mitochondrial Dysfunction, Oxidative Stress and Release of Apoptotic Proteins during Nimesulide-Hepatotoxicity in Rats

Nimesulide, an anti-inflammatory and analgesic drug, is reported to cause severe hepatotoxicity. In this study, molecular mechanisms involved in deranged oxidant-antioxidant homeostasis and mitochondrial dysfunction during nimesulide-induced hepatotoxicity and its attenuation by plant derived terpen...

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Detalles Bibliográficos
Autores principales: Singh, Brijesh Kumar, Tripathi, Madhulika, Chaudhari, Bhushan P., Pandey, Pramod K., Kakkar, Poonam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317927/
https://www.ncbi.nlm.nih.gov/pubmed/22509279
http://dx.doi.org/10.1371/journal.pone.0034200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317927/
https://www.ncbi.nlm.nih.gov/pubmed/22509279
http://dx.doi.org/10.1371/journal.pone.0034200

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