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A Human PrM Antibody That Recognizes a Novel Cryptic Epitope on Dengue E Glycoprotein
Dengue virus (DENV) is a major mosquito-borne pathogen infecting up to 100 million people each year; so far no effective treatment or vaccines are available. Recently, highly cross-reactive and infection-enhancing pre-membrane (prM)-specific antibodies were found to dominate the anti-DENV immune res...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317930/ https://www.ncbi.nlm.nih.gov/pubmed/22509258 http://dx.doi.org/10.1371/journal.pone.0033451 |