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A Human PrM Antibody That Recognizes a Novel Cryptic Epitope on Dengue E Glycoprotein
Dengue virus (DENV) is a major mosquito-borne pathogen infecting up to 100 million people each year; so far no effective treatment or vaccines are available. Recently, highly cross-reactive and infection-enhancing pre-membrane (prM)-specific antibodies were found to dominate the anti-DENV immune res...
Autores principales: | Chan, Annie Hoi Yi, Tan, Hwee Cheng, Chow, Angelia Yee, Lim, Angeline Pei Chiew, Lok, Shee Mei, Moreland, Nicole J., Vasudevan, Subhash G., MacAry, Paul A., Ooi, Eng Eong, Hanson, Brendon J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317930/ https://www.ncbi.nlm.nih.gov/pubmed/22509258 http://dx.doi.org/10.1371/journal.pone.0033451 |
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