Prevalence, Distribution and Functional Significance of the −237C to T Polymorphism in the IL-12Rβ2 Promoter in Indian Tuberculosis Patients

Cytokine/cytokine receptor gene polymorphisms related to structure/expression could impact immune response. Hence, the −237 polymorphic site in the 5′ promoter region of the IL-12Rβ2 (SNP ID: rs11810249) gene associated with the AP-4 transcription motif GAGCTG, was examined. Amplicons encompassing t...

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Detalles Bibliográficos
Autores principales: Verma, Vikas Kumar, Taneja, Vibha, Jaiswal, Anand, Sharma, Sangeeta, Behera, Digamber, Sreenivas, Vishnubhatla, Chauhan, Shyam Singh, Prasad, Hanumanthappa Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317943/
https://www.ncbi.nlm.nih.gov/pubmed/22509293
http://dx.doi.org/10.1371/journal.pone.0034355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317943/
https://www.ncbi.nlm.nih.gov/pubmed/22509293
http://dx.doi.org/10.1371/journal.pone.0034355

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