Nicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from Pellagra

Compartmentalized redox faults are common to ageing diseases. Dietary constituents are catabolized to NAD(H) donating electrons producing proton-based bioenergy in coevolved, cross-species and cross-organ networks. Nicotinamide and NAD deficiency from poor diet or high expenditure causes pellagra, a...

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Detalles Bibliográficos
Autores principales: Williams, Adrian C., Hill, Lisa J., Ramsden, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318212/
https://www.ncbi.nlm.nih.gov/pubmed/22536229
http://dx.doi.org/10.1155/2012/302875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318212/
https://www.ncbi.nlm.nih.gov/pubmed/22536229
http://dx.doi.org/10.1155/2012/302875

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