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The Role of the N-Domain in the ATPase Activity of the Mammalian AAA ATPase p97/VCP

p97/valosin-containing protein (VCP) is a type II ATPase associated with various cellular activities that forms a homohexamer with each protomer containing an N-terminal domain (N-domain); two ATPase domains, D1 and D2; and a disordered C-terminal region. Little is known about the role of the N-doma...

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Detalles Bibliográficos
Autores principales: Niwa, Hajime, Ewens, Caroline A., Tsang, Chun, Yeung, Heidi O., Zhang, Xiaodong, Freemont, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318706/
https://www.ncbi.nlm.nih.gov/pubmed/22270372
http://dx.doi.org/10.1074/jbc.M111.302778