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The Role of the N-Domain in the ATPase Activity of the Mammalian AAA ATPase p97/VCP
p97/valosin-containing protein (VCP) is a type II ATPase associated with various cellular activities that forms a homohexamer with each protomer containing an N-terminal domain (N-domain); two ATPase domains, D1 and D2; and a disordered C-terminal region. Little is known about the role of the N-doma...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318706/ https://www.ncbi.nlm.nih.gov/pubmed/22270372 http://dx.doi.org/10.1074/jbc.M111.302778 |