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Phosphatidylinositol 4-Kinase IIIβ Is Required for Severe Acute Respiratory Syndrome Coronavirus Spike-mediated Cell Entry

Phosphatidylinositol kinases (PI kinases) play an important role in the life cycle of several viruses after infection. Using gene knockdown technology, we demonstrate that phosphatidylinositol 4-kinase IIIβ (PI4KB) is required for cellular entry by pseudoviruses bearing the severe acute respiratory...

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Detalles Bibliográficos
Autores principales: Yang, Ning, Ma, Ping, Lang, Jianshe, Zhang, Yanli, Deng, Jiejie, Ju, Xiangwu, Zhang, Gongyi, Jiang, Chengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318727/
https://www.ncbi.nlm.nih.gov/pubmed/22253445
http://dx.doi.org/10.1074/jbc.M111.312561