Cargando…
Estradiol Triggers Sonic-hedgehog–induced Angiogenesis During Peripheral Nerve Regeneration by Downregulating Hedgehog-interacting Protein
Both estradiol (E2) and Sonic Hedgehog (Shh) contribute to angiogenesis and nerve regeneration. Here, we investigated whether E2 improves the recovery of injured nerves by downregulating the Shh-inhibitor Hedgehog-interacting Protein (HIP) and increasing Shh-induced angiogenesis. Mice were treated w...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319330/ https://www.ncbi.nlm.nih.gov/pubmed/22330336 http://dx.doi.org/10.1038/labinvest.2012.6 |