Cleavage of pyrene-stabilized RNA bulge loops by trans-(±)-cyclohexane-1,2-diamine

Chemical agents that cleave HIV genome can be potentially used for anti-HIV therapy. In this report, the cleavage of the upper stem-loop region of HIV-1 TAR RNA was studied in a variety of buffers containing organic catalysts. trans-(±)-Cyclohexane-1,2-diamine was found to cleave the RNA with the hi...

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Detalles Bibliográficos
Autores principales: Patel, Sejal, Rana, Jagruti, Roy, Jyoti, Huang, Haidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319420/
https://www.ncbi.nlm.nih.gov/pubmed/22244351
http://dx.doi.org/10.1186/1752-153X-6-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319420/
https://www.ncbi.nlm.nih.gov/pubmed/22244351
http://dx.doi.org/10.1186/1752-153X-6-3

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