Comparative Analysis of Mycobacterium tuberculosis pe and ppe Genes Reveals High Sequence Variation and an Apparent Absence of Selective Constraints

Mycobacterium tuberculosis complex (MTBC) genomes contain 2 large gene families termed pe and ppe. The function of pe/ppe proteins remains enigmatic but studies suggest that they are secreted or cell surface associated and are involved in bacterial virulence. Previous studies have also shown that so...

Descripción completa

Detalles Bibliográficos
Autores principales: McEvoy, Christopher R. E., Cloete, Ruben, Müller, Borna, Schürch, Anita C., van Helden, Paul D., Gagneux, Sebastien, Warren, Robin M., Gey van Pittius, Nicolaas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319526/
https://www.ncbi.nlm.nih.gov/pubmed/22496726
http://dx.doi.org/10.1371/journal.pone.0030593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319526/
https://www.ncbi.nlm.nih.gov/pubmed/22496726
http://dx.doi.org/10.1371/journal.pone.0030593

Ejemplares similares