A Preclinical Assessment of Neural Stem Cells as Delivery Vehicles for Anti-Amyloid Therapeutics

Transplantation of neural stems cells (NSCs) could be a useful means to deliver biologic therapeutics for late-stage Alzheimer's disease (AD). In this study, we conducted a small preclinical investigation of whether NSCs could be modified to express metalloproteinase 9 (MMP9), a secreted protea...

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Detalles Bibliográficos
Autores principales: Njie, eMalick G., Kantorovich, Svetlana, Astary, Garrett W., Green, Cameron, Zheng, Tong, Semple-Rowland, Susan L., Steindler, Dennis A., Sarntinoranont, Malisa, Streit, Wolfgang J., Borchelt, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319561/
https://www.ncbi.nlm.nih.gov/pubmed/22496779
http://dx.doi.org/10.1371/journal.pone.0034097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319561/
https://www.ncbi.nlm.nih.gov/pubmed/22496779
http://dx.doi.org/10.1371/journal.pone.0034097

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