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A Preclinical Assessment of Neural Stem Cells as Delivery Vehicles for Anti-Amyloid Therapeutics

Transplantation of neural stems cells (NSCs) could be a useful means to deliver biologic therapeutics for late-stage Alzheimer's disease (AD). In this study, we conducted a small preclinical investigation of whether NSCs could be modified to express metalloproteinase 9 (MMP9), a secreted protea...

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Detalles Bibliográficos
Autores principales:	Njie, eMalick G., Kantorovich, Svetlana, Astary, Garrett W., Green, Cameron, Zheng, Tong, Semple-Rowland, Susan L., Steindler, Dennis A., Sarntinoranont, Malisa, Streit, Wolfgang J., Borchelt, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319561/ https://www.ncbi.nlm.nih.gov/pubmed/22496779 http://dx.doi.org/10.1371/journal.pone.0034097

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