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An Unexpected Function of the Prader-Willi Syndrome Imprinting Center in Maternal Imprinting in Mice

Genomic imprinting is a phenomenon that some genes are expressed differentially according to the parent of origin. Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are neurobehavioral disorders caused by deficiency of imprinted gene expression from paternal and maternal chromosome 15q11–q13, r...

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Detalles Bibliográficos
Autores principales: Wu, Mei-Yi, Jiang, Ming, Zhai, Xiaodong, Beaudet, Arthur L., Wu, Ray-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319576/
https://www.ncbi.nlm.nih.gov/pubmed/22496793
http://dx.doi.org/10.1371/journal.pone.0034348