Dual Anti-OX40/IL-2 Therapy Augments Tumor Immunotherapy via IL-2R-Mediated Regulation of OX40 Expression

The provision of T cell co-stimulation via members of the TNFR super-family, including OX40 (CD134) and 4-1BB (CD137), provides critical signals that promote T cell survival and differentiation. Recent studies have demonstrated that ligation of OX40 can augment T cell-mediated anti-tumor immunity in...

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Detalles Bibliográficos
Autores principales: Redmond, William L., Triplett, Todd, Floyd, Kevin, Weinberg, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319580/
https://www.ncbi.nlm.nih.gov/pubmed/22496812
http://dx.doi.org/10.1371/journal.pone.0034467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319580/
https://www.ncbi.nlm.nih.gov/pubmed/22496812
http://dx.doi.org/10.1371/journal.pone.0034467

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